This is a comprehensive and up-to-date account of the structures and physical chemistry properties of nucleic acids, with special emphasis on biological function. The book has been carefully organised to meet the needs of molecular biologists, physical biochemists and physical chemists with only a basic understanding of physical chemistry and molecular biology. Nucleic Acids will serve as a textbook in physical biochemistry and biophysical chemistry classes, as well as a supplemental text in courses on nucleic acid biochemistry or molecular biology, and as a personal reference for students and researchers in these fields.
Organised according to a systematic consideration of techniques used in the study of nucleic acid structure and properties
Key topics such as proteinDNA and proteindrug complexes, conformational transitions, characterisation of nucleic acids by gel and solution techniques and behaviour of supercoiled DNA are covered in great detail as veritable minimonographs
Heavily illustrated with diagrams, graphs and molecular structures, including nearly two dozen colour figures
Includes numerous figures, tables and an extensive bibiliography to facilitate use as a reference volume
Victor A. Bloomfield
DNA Nucleotide biochemistry biology chemistry molecular biology nucleic acid protein