Tissue Engineering Methods and Protocols

Beschreibung

Jeffrey Morgan and Martin Yarmush bring together in Tissue Engineering the first major collection of cutting-edge methods developed and used by leading researchers in the tissue engineering field. These hands-on experts describe easily reproducible protocols for the production and evaluation of polymers, scaffolds, and composites, as well as methods for the isolation, culture, and analysis of cells, including the combination of cells with a variety of materials or devices. Quantitative methods designed to assess cell performance and cell function that will also illuminate our understanding of cellular processes and the cellular response to the chemical and mechanical environment of a functional organ/tissue are also offered.

Tissue Engineering provides researchers with detailed methods and protocols covering a comprehensive range of key technologies and techniques used by leaders in tissue engineering research. Its interdisciplinary methods-drawn from the life sciences, engineering, and clinical medicine-are already making a significant contribution to the development of new and effective treatments for both organ and tissue defects.



In recent years, the field of tissue engineering has begun, in part, to c- lesce around the important clinical goal of developing substitutes or repla- ments for defective tissues or organs. These efforts are focused on many tissues including skin, cartilage, liver, pancreas, bone, blood, muscle, the vascu- ture, and nerves. There is a staggering medical need for new and effective treatments for acquired as well as inherited defects of organs/tissues. Tissue engineering is at the interface of the life sciences, engineering, and clinical medicine and so draws upon advances in cell and molecular biology, mate- als sciences, and surgery, as well as chemical and mechanical engineering. Such an interdisciplinary field requires a broad knowledge base as well as the use of a wide assortment of methods and approaches. It is hoped that by bringing together these protocols, this book will help to form connections - tween the different disciplines and further stimulate the synergism underlying the foundation of the tissue engineering field.

Autor*in

Jeffrey R. Morgan

Stimmen zu »Tissue Engineering Methods and Protocols«

"...will provide a very valuable laboratory aid for any researcher who wishes to enter the field. For the experienced cell biologist there are some gems of collected wisdom which he or she should find inspiring...a thoroughly recommended lab-bench book. . .This book should be in the library of every surgical research department. It is an excellent "how-to-do-it" work."-Journal of The Royal College of Surgeons of Edinburgh

"This book, well-edited by Morgan and Yarmush, contains a nearly exhaustive series of protocols related to biomaterials, cells, composites of cells and biomaterials, and measurement techniques. The editors are known and respected in the field, and, as such, were able to attract some of the stalwart tissue engineering investigators. . . an indispensable aid to students and seasoned investigators in tissue engineering."-FEBS Letters

"...a weighty tome of over 600 pages which can really be considered a tour de force, a great achievement in both organizational and editing skills from Morgan and Yarmush, the editors. I found several of the contributions outstanding...a useful acquisition."-Cell Biology International


()

Details

Link teilen