Stroke Genetics
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Beschreibung
Over the last decade there has been a substantial increase in our understanding of the genetic basis of common disorders such as stroke. Stroke Genetics is designed to give the reader an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genome-wide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed. Stroke Genetics benefits from the contribution of renowned experts from throughout the world who have been intimately involved in unraveling the genetic etiology of stroke. Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics.
Over the last decade there has been a substantial increase in our understanding of the genetic basis of common disorders such as stroke. Stroke Genetics is designed to give the reader an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genome-wide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed. Stroke Genetics benefits from the contribution of renowned experts from throughout the world who have been intimately involved in unraveling the genetic etiology of stroke. Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics.
Summarizes the current state of knowledge in stroke genetics, using stroke as a paradigm in understanding other complex disorders thereby providing a single authoritative source on the molecular basis of stroke as well as for understanding the genetic basis of other common diseases Brings together the leading experts from around the world Tables and diagrams present information in a graphical form to assist the reader in quickly understanding key concepts Contextualizes genetic technologies to assist the reader in understanding the implications of fast-developing new fields Addresses in detail important monogenic causes of stroke Includes supplementary material: sn.pub/extras
Autor*in
Pankaj Sharma
Themen in »Stroke Genetics«
CADASIL Fabry GWAS Genetics Genome Hypertension MELAS Stem Cell Stroke cerebral hemmorhage
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From the reviews:
“This text reviews genetics of cerebrovascular diseases … . It covers the pathophysiology of occlusive small vessel disease and arteriopathies. It covers Fabry’s Disease, Amyloidosis, MELAS, etc., etc. It covers the imaging, pathophysiology, treatment, and complications for ischemia and hemorrhaging. I recommend this text for neurosurgeons, neurologists, physiologists, genetic investigators, and those with an interest in vascular diseases affecting the cerebrum.” (Joseph J. Grenier, Amazon.com, May, 2014)()