Mechanisms and Biological Significance of Pulsatile Hormone Secretion

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Mechanisms and Biological Significance of Pulsatile Hormone Secretion Chair: Johannes D. Veldhuis 2000 Many endocrine systems use the intermittent or pulsatile release of hormones to transmit complex information into cellular compartments of the body. Although the actual concentration of a particular hormone is clearly important in endocrine signalling, valuable information is also encoded by the frequency of hormone release. In addition, circadian and seasonal rhythmicity also characterize the action of many hormones. This exciting book brings together an international group of basic and clinical scientists to discuss the importance of pulsatile signalling in the induction of biological responses. Coverage includes the basic mechanisms involved in hormone pulsatility, the significance of pulsatility in normal and disease conditions, the relevance to circadian rhythms, changes with ageing, and detailed consideration of specific peptide hormone systems. This book includes papers by many leading experts in this field, together with extensive discussions which reveal much new and exciting work in this area and identify promising new research directions.
Dieses Buch beschäftigt sich mit grundlegenden Mechanismen der zeitlichen Steuerung unseres Organismus, die den circadianen und den jahreszeitlichen Lebensrhythmus bestimmen. Diskutiert werden die wichtigsten Peptidhormonsysteme, die Bedeutung der Rhythmen hinsichtlich verschiedener Chemotherapien, die Pathologie des Circadianrhythmus und Veränderungen im Laufe der Alterung des Organismus. (12/99)

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Biowissenschaften Cell & Molecular Biology Endocrinology Endokrinologie Life Sciences Medical Science Medizin Zell- u. Molekularbiologie Zellbiologie

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"This book provides a comprehensive and excellent summary of our state of knowledge," (Cell Biology International, May 2001) "This outstanding text should stimulate further research on pulsatile hormone secretion that will enhance both biomedical science and clinical treatments of hormone-related disorders" (Trends in Endocrinology & Metabolism, August 2001)
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