Microbial Proteomics
Functional Biology of Whole Organisms
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Beschreibung
Discover important lessons learned about whole organism biologyvia microbial proteomics
This text provides an exhaustive analysis and presentation ofcurrent research in the field of microbial proteomics, with anemphasis on new developments and applications and future directionsin research. The editors and authors show how and why the relativesimplicity of microbes has made them attractive targets forextensive experimental manipulation in a quest for both improveddisease prevention and treatment and an improved understanding ofwhole organism functional biology. In particular, the textdemonstrates how microbial proteomic analyses can aid in drugdiscovery, including identification of new targets, noveldiagnostic markers, and lead optimization.
Each chapter is written by one or more leading experts in thefield and carefully edited to ensure a consistent and thoroughapproach throughout. Methods, technologies, and tools associatedwith the most promising approaches are stressed. Key topics coveredinclude:
* Microbial pathogenesis at the proteome level
* Whole cell modeling
* Structural proteomics and computational analysis
* Biomolecular interactions
* Physiological proteomics
* Metabolic reconstruction using proteomics data
While presenting the practical utility of proteomics data, thetext is also clear on the field's current limitations, pointing toareas where further investigation is needed.
Offering a state-of-the-art perspective from internationallyrecognized experts, this text is ideally suited for researchers andstudents across the gamut of genomic sciences, includingbiochemistry, microbiology, molecular biology, genetics, biomedicaland pharmaceutical sciences, biotechnology, and veterinaryscience.
Autor*in
Ian Humphery-Smith
Themen in »Microbial Proteomics«
Biologie Biotechnologie Biotechnologie i. d. Chemie Biotechnology Biowissenschaften Chemie Chemistry Genomforschung u. Proteomik Genomics & Proteomics Life Sciences Microbiology & Virology Mikrobiologie u. Virologie Proteomics
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"The authors have provided a thorough overview of what is still a relatively new field of study." (CHOICE, January 2007)
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