Microarray Quality Control
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Beschreibung
Microarray technology provides researchers in the life scienceswith a revolutionary tool for measuring gene expression. However,this highly developed process involves multiple steps, from sampleselection to data analysis, each susceptible to potentially costlyerrors. Without sound quality control, experimental microarrays mayproduce useless or, even worse, misleading results.
Microarray Quality Control provides a comprehensive resource forensuring quality control in every step of this complex process.From experimental design to data processing, analysis, andinterpretation, the emphasis in this text remains on practicaladvice for each stage of planning and running a microarray study.Chapters cover:
* Quality of biological samples
* Quality of DNA
* Hybridization protocols Scanning
* Data acquisition
* Image analysis
* Data analysis
Written for the broad group of workers-biologists, mathematicians,statisticians, engineers, physicians, and computationalscientists-involved in microarray studies, Microarray QualityControl features a straightforward style easily accessed by variousdisciplines. Useful checklists and tips help ensure the integrityof results, and each chapter contains a thorough review ofpertinent literature.
The only complete, systematic treatment of the topic available,Microarray Quality Control offers students and practitioners aninvaluable resource for improving experimental quality andefficiency.
Autor*in
Wei Zhang
Themen in »Microarray Quality Control«
Bioinformatics & Computational Biology Bioinformatik u. Computersimulationen in der Biowissenschaften Biotechnologie i. d. Chemie Biotechnology Biowissenschaften Cell & Molecular Biology Chemie Chemistry Life Sciences Molekularbiologie Zell- u. Molekularbiologie
Stimmen zu »Microarray Quality Control«
"...a thought-provoking book...highly useful tostatisticians, biologists, engineers, medical researchers, andmedical scientists." (Journal of Statistical Computation andSimulation, September 2005)
"The book may be recommended for all researchers and studentsworking with the DNA microarray technology" (Annals ofBiomedical Engineering, June 2005)
"...a useful source of ideas and potential issues." (Journalof the American Statistical Association, June 2005)
"This book is recommended [for] all libraries servingresearchers using high-throughput techniques." (E-STREAMS,March 2005)
"...an essential laboratory resource for scientistsstudying gene regulation and for all experimental biologistsinterested in the emerging practical applications ofmicroarrays." (Engineering in Life Sciences, Vol.5,No.5, 2004)
"...offers practical guidance for each stage of planning andexecution of microarray studies..." (Genetic EngineeringNews, Vol. 24, No. 6, March 15, 2004)
"...the breadth of issues encompassed by quality control inmicroarray studies are covered...a valuable systematictreatment of microarray quality control." (Drug Discovery andDevelopment, March 2004)
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