An indispensable tool for those working at the front lines of newdrug development
Written for busy professionals at the forefront of new drugdevelopment, Drug Delivery gets readers quickly up to speed on boththe principles and latest applications in the increasinglyimportant field of drug delivery.
Recent developments in such areas as combinatorial chemistry,proteomics, and genomics have revolutionized researchers' abilityto rapidly identify and synthesize new pharmacological compounds.However, delivery-related properties remain a significant reasonfor clinical trial failures.
Bringing together contributions by leading international experts,Drug Delivery covers the entire field in a systematic but conciseway. It begins with an in-depth review of key fundamentals, such asphysiochemical and biological barriers; drug delivery pathways;metabolism; drug formulation; pharmacokinetic and pharmacodynamicissues; and more. The remainder of the book is devoted to thesystematic examination-including overviews, timely examples, andextensive references-of a host of specific subjects,including:
* Receptor-mediated drug delivery
* Prodrug delivery approaches
* Oral protein and peptide drug delivery
* Gene therapy and gene delivery
* Ultrasound-mediated drug delivery
* Polycationic peptides and proteins in drug delivery
* Pulmonary drug delivery
* Antibody-directed drug delivery
* Efflux transporters in drug excretion
* Intellectual property issues in drug delivery
Binghe Wang
Biochemie Biochemie u. Chemische Biologie Biochemistry (Chemical Biology) Chemie Chemistry Drug Formulation & Delivery Wirkstoffformulierung, Wirkstofftransport Wirkstofffreisetzung
"...this text provides an excellentoverview..." (Chemistry & Industry, No 24,19th December 2005)
"...a concise but highly readable text...Irecommend this well presented and well written book..."(Chemistry World, Vol. 2 (10), October 2005)
"...the broad overview of drug delivery technology presented inthis book makes it well suited as a reference volume..."(E-STREAMS, September 2005)
"...systematically examines various subject areas importantto drug delivery." (Drug Discovery & Development, June2005)
()