Human Polyomaviruses
Molecular and Clinical perspectives
Edited by Kamel Khalili and Gerald L. Stoner
Our understanding of human polyomaviruses has evolved profoundly inthe last fifteen years, creating an urgent need for an updatedresource. Drs. Khalili and Stoner have collected the contributionsof renowned researchers and clinicians in this cutting-edge volume.
Human Polyomaviruses: Molecular and Clinical Perspectivespresents in-depth analyses, comprehensive reviews, and timelyassessments of recent discoveries and ongoing controversies focusedon these important viral pathogens. Beginning with an historicalperspective, this book covers up-to-date investigations into themolecular biology and pathogenesis of human polyomaviruses. Allaspects of these persistent infections are subsequently covered,including clinical issues, from diagnosis to information ontreatment and drug trials. Central topics are:
* BK virus
* JC virus
* Simian virus 40 (SV40) and its potential as a humanpathogen
* Progressive multifocal leukoencephalopathy (PML)
This reference is a superb indoctrination for graduate students,medical students, high-level undergraduates, and anyone engaged inthe study of DNA viruses and their molecular biology, evolution,transmission, and pathological potential.
Kamel Khalili
Biowissenschaften Cell & Molecular Biology Immunologie Immunology Life Sciences Medical Science Medizin Molekularbiologie Pathogenese Polyomaviren Virologie Zell- u. Molekularbiologie
"...an excellent overview of the human polymaviruses. The book isbroad, yet detailed in coverage." (Doody's Health Services, January20, 2002)
"comprehensive", "well-indexed", "well-referenced", and "containsexcellent color plates of histopathology" (Journal ofNeuropathology and Experimental Neurology, April 2002)
"this book, at over 650 pages, is indeed comprehensive" "a usefulreference book for interested clinical neurologists, virologistsand research scientists" (Microbiology Today, Vol. 29, May 2002)"This multi-authored book provides a fascinating account of thediscovery of JC virus, BK virus and the related Simian polyomavirusSV40, as well as their associated diseases, spanning the past 50years...Moreover, this unique book really provides a roadmap forfuture research...It will certainly appeal to all medical andgraduate students, to infectious diseases specialists, and thoseinvolved in the field of DNA virus research."
--Igor J. Koralnik, M.D., Harvard Medical School)
"It has become necessary to summarize and organize [the] growingbody of information about polyomaviruses for the benefit of medicalstudents, general practitioners, as well as specialists [...] HumanPolyomaviruses: Molecular and Clinical Perspectives fills this needadmirably [...] Coverage of topics is thorough, and includes cogentdiscussions of all controversies in the field, as well as acomprehensive bibliography [...] This book should provide for veryengaging reading to any curious mind interested in viral diseasesof man."
--Parmjeet S. Randhawa, M.D., University of Pittsburgh MedicalCenter
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