Solid-Phase Organic Syntheses, Volume 1
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Beschreibung
The rapid expansion of combinatorial chemistry has renewed interestin solid-phase organic synthesis, a method that lends itself wellto creating and screening large numbers of lead compounds.Solid-Phase Organic Syntheses, Volume 1 is the first volume in aseries that will be updated annually, filling a gap in the existingchemical literature. Providing information previously unavailablefrom a single resource, this series is dedicated to providingresearchers in the field with validated and tested methods for thesolid-phase synthesis of interesting and biologically relevantmolecules.
Solid-phase methods will virtually always be invented forapplication in combinatorial organic synthesis. To meet thesespecific needs, Solid-Phase Organic Syntheses, Volume 1 focuses ona single type of synthetic transformation accomplished on solidsupport, and indicates how procedures are optimized to work with astructurally-wide variety of reagents. Written by recognizedleaders in the field who review and test all chemical protocolsbefore publication, organic transformations are organized by typeof compound synthesized and reaction type.
For the first time, experimental details for proven solid-phasesynthetic molecules are collected in a single, invaluable resource.Solid-Phase Organic Syntheses, Volume 1 provides combinatorialchemists and researchers in organic chemistry and medicinalchemistry with the tools and descriptive protocols to achievesyntheses of desired compounds using a variety of solid supportsand reagents.
Autor*in
Anthony W. Czarnik
Themen in »Solid-Phase Organic Syntheses, Volume 1«
Chemie Chemistry Festkörper Methods - Synthesis & Techniques Organische Chemie / Methoden, Synthesen, Verfahren Organische Synthese Pharmaceutical & Medicinal Chemistry Pharmazeutische u. Medizinische Chemie
Stimmen zu »Solid-Phase Organic Syntheses, Volume 1«
"Practicing organic chemists.rely on the series.OrganicSynthesis.as a compendium of tried and tested methods for makingorganic compounds. The new field of solid phase organicsynthesis.needs a similar reference work. Solid Phase OrganicSyntheses was created to fill this need." (Organic Process Research& Development Journal, Vol. 5, No. 6, November 2001)
"This series should become as indispensable to researchers in thefield of solid-phase organic synthesis as OS has been to the fieldof solution-phase organic synthesis." (Journal of MedicinalChemistry, Vol. 44, No. 21, 2001)
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