Oljan Repic Repic Principles of Process Research and Chemical Development in the Pharmaceutical Industry

Principles of Process Research and Chemical Development in the Pharmaceutical Industry

von Oljan Repic

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Beschreibung

This text discusses the functions of Process R&D (research and development), which involves the method of transforming a research synthetic procedure into a plant process and the key aspects of a synthesis that must be considered when scaling up a process. Topics consist of: basic principles of chemical development; techniques for the minimization of by-product impurities; criteria for cost-effective synthesis of enantiopure compounds by resolutions; asymmetric synthesis, and "chiral pool" strategy; synthesis for labeling substances with hydrogen or carbon isotopes; and last, licensing.

Autor*in

Oljan Repic

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Organische Chemie Pharmazeutische Chemie Pharmazeutische Industrie Technik / Chemische Technik

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Details

ISBN: 9780471165163
Verlag: John Wiley & Sons
Erscheinung: 16.01.1998

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