Development of the Cardiac Conduction System
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Beschreibung
The pacemaking and conduction system (PCS) is vital for generatingand synchronizing the heart beat. Dysfunction of this systemcan be a direct cause of cardiac conduction disturbance,arrhythmias and sudden cardiac death. A wealth of information hasbeen collected over many years on the unique histological,morphological and phenotypic characteristics of specialized cardiactissues. The cellular and molecular mechanisms that governdevelopment of the PCS are now starting to be understood.
This book draws together contributions from an international andinterdisciplinary group of experts working on both basic andclinical aspects of cardiac development. It features reviews of thestructure and function of the developing PCS, discussion of themolecular and cellular mechanisms regulating embryologicaldevelopment of this system and studies on the fundamentalbasis of PCS pathology. The book also considers how noveltherapeutic interventions based on understanding of thedevelopmental biology of cardiac pacemaking and conduction tissuesmight ultimately impact on clinical medicine.
Autor*in
Derek J. Chadwick
Themen in »Development of the Cardiac Conduction System«
Anatomie u. Physiologie Anatomy & Physiology Biologie Biowissenschaften Cardiovascular Disease Genetics Genetik Kardiovaskuläre Erkrankung Kardiovaskuläre Erkrankungen Life Sciences Medical Science Medizin