Recent studies have shown that the heart possesses an intrinsicrenin angiotensin system that is controlled by tissue-specificparameters that are activated by biomechanical stress. This bookreviews the latest information on the way in which both the plasmaand cardiac renin angiotensin systems affect heart function.
It covers the cell and molecular biology of these systems, withcontributions on renin synthesis, uptake and the intracellularsignalling pathways. Particular insight comes from transgenic mousemodels in which either mouse or human genes for various componentsof the renin angiotensin system are expressed. Other topics coveredinclude wound healing as well as the trophic effects ofaldosterone.
* Contains the most recent findings on the renin angiotensinsystem and the heart
* Written by an international team of distinguishedscientists
* Covers both the cellular and molecular basis of the reninangiotensin system and the clinical relevance of this research
Walmor C. De Mello
Cardiovascular Disease Endocrinology Endokrinologie Kardiovaskuläre Erkrankung Kardiovaskuläre Erkrankungen Medical Science Medizin
"Recommended for the intended audience of cardiologists, nephrologists, cell and molecular biologists, physiologists, pathologists and pharmacologists as well as medical libraries." (E-STREAMS, May 2005)
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