Quantitative MRI of the Brain

Beschreibung

This indispensable 'how to' manual of quantitative MR is essential for anyone who wants to use the gamut of modern quantitative methods to measure the effects of neurological disease, its progression, and its response to treatment. The text opens with a section on concepts which explore the principles of good practice in quantification, including quality assurance, MR data collection, and analysis aspects. Current limits are discussed in detail, and solutions proposed. A chapter on each of the major physical quantities follows (including proton density, T1, T2, diffusion, magnetization transfer, spectroscopy, functional MRI and arterial spin labeling). The physical principles behind each quantity are given followed by their biological significance, practical techniques for measuring the quantity imperfections that can arise in the measuring process, and an extensive survey of clinical applications of that quantity. The pathological correlations with the MR quantities are also discussed.

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Paul Tofts

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Biochemie Magnetische Resonanz Molekularbiologie

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