Biological Chemistry of Arsenic, Antimony and Bismuth

Beschreibung

Arsenic, antimony and bismuth, three related elements of group 15, are all found in trace quantities in nature and have interesting biological properties and uses. While arsenic is most well known as a poison, and indeed the contamination of groundwater by arsenic is becoming a major health problem in Asia, it also has uses for the treatment of blood cancer and has long been used in traditional Chinese medicine. Antimony and bismuth compounds are used in clinics for the treatment of parasitic and bacterial infections. Biological Chemistry of Arsenic, Antimony and Bismuth is an essential overview of the biological chemistry of these three elements, with contributions from an international panel of experts. Topics covered include: * the chemistry and biological chemistry of arsenic, antimony and bismuth * the interaction of arsenic with macromolecules and its relationship to carcinogenesis * metallomics research related to arsenic * arsenic in traditional Chinese medicine * microbial transformations of arsenic in aquifers * biomethylation of arsenic, antimony and bismuth * metalloid transport systems * bismuth complexes of porphyrins and their potential in medical applications * Helicobacter pylori and bismuth * application of arsenic trioxide therapy for patients with leukaemia * anti-cancer activity of molecular compounds of arsenic, antimony, and bismuth * radiobismuth for therapy * genetic toxicology of arsenic and antimony * metalloproteomics of arsenic-, antimony- and bismuth-based drugs Biological Chemistry of Arsenic, Antimony and Bismuth conveys the essential aspects of the bioinorganic chemistry of these three elements, providing a valuable complement to more general bioinorganic chemistry texts and more specialized topical reviews. It will find a place on the bookshelves of practitioners, researchers and students working in bioinorganic chemistry, medicinal chemistry and biochemistry.
Arsenic, antimony and bismuth, three related elements of group 15, are all found in trace quantities in nature and have interesting biological properties and uses. While arsenic is most well known as a poison - and indeed the contamination of groundwater by arsenic is becoming a major health problem in Asia - it also has uses for the treatment of blood cancer and has long been used in traditional chinese medicine. Antimony and bismuth compounds are used in the clinic for the treatment of parasitic and bacterial infections. Biological Chemistry of Arsenic, Antimony and Bismuth is an essential overview of the biological chemistry of these three elements, with contributions from an international panel of experts. Topics covered include: * chemistry of As, Sb and Bi * biological chemistry of arsenic * biological chemistry of Sb and Bi * arsenic and antimony speciation in environmental and biological samples * arsenic in traditional chinese medicine * arsenic in aquifers * biomethylation of As, Sb and Bi * uptake of metalloids by cells * bismuth complexes of porphyrins and their potential in medical applications * Helicobacter pylori and bismuth * metabolism of arsenic trioxide in blood of the acute promyelocytic leukemia patients * anticancer properties of As, Sb and Bi * radio-Bi in cancer therapy * genotoxicity of As, Sb and Bi * metallomics as a new technique for As, Sb and Bi * metalloproteomics for As, Sb and Bi Biological Chemistry of Arsenic, Antimony and Bismuth conveys the essential aspects of the bioinorganic chemistry of these three elements, making this book a valuable complement to more general bioinorganic chemistry texts and more specialized topical reviews. It will find a place on the bookshelves of practitioners, researchers and students working in bioinorganic chemistry and medicinal chemistry.

Autor*in

Hongzhe Sun

Themen in »Biological Chemistry of Arsenic, Antimony and Bismuth«

Bioanorganische Chemie Biochemie Biochemie u. Chemische Biologie Biochemistry (Chemical Biology) Bioinorganic Chemistry Chemie Chemistry Pharmaceutical & Medicinal Chemistry Pharmazeutische u. Medizinische Chemie

Stimmen zu »Biological Chemistry of Arsenic, Antimony and Bismuth«

Details

Link teilen