Chiral Separation Methods for Pharmaceutical and Biotechnological Products
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Beschreibung
Discusses chiral separations and offers guidance for selectingthe optimum method for desired results
Chiral separations represent the most intriguing and, by somemeasures, most difficultseparations of chemical compounds. Thisbook provides researchers and students an under-standing of chiralseparations and offers a convenient route to selecting the bestseparation method, saving considerable time and cost in productdevelopment.
Considering chiral separations in the biotechnological andpharmaceutical industries, as well as for food applications, Dr.Ahuja provides insights into a broad range of topics. Opening witha broad overview of chiral separations, regulatory considerationsin drug product development, and basic issues in methoddevelopment, the book:
* Covers a variety of modern methods such as gas chromatography,high performance liquid chromatography, supercritical fluidchromatography, and capillary electrophoresis
* Deals with the impact of chirality on the biological activity ofsmall and large molecules
* Provides detailed information on useful chiral stationary phases(CSPs) for HPLC
* Includes handy information on selection of an appropriate CSP,including mechanistic studies
* Offers strategies for fast method development with HPLC, SFC,and CE
* Discusses preparatory methods utilized in the pharmaceuticalindustry
With in-depth discussions of the current state of the field aswell as suggestions to assist future developments, ChiralSeparation Methods for Pharmaceutical and BiotechnologicalProducts is an essential text for laboratory investigators,managers, and regulators who are involved in chiral separations inthe pharmaceutical industry, as well as students preparing forcareers in these fields.
Autor*in
Satinder Ahuja
Themen in »Chiral Separation Methods for Pharmaceutical and Biotechnological Products«
Analytical Chemistry Analytische Chemie Biotechnologie Biotechnologie i. d. Chemie Biotechnology Chemie Chemistry Chiralität (Chemie) Pharmaceutical & Medicinal Chemistry Pharmazeutische u. Medizinische Chemie
Stimmen zu »Chiral Separation Methods for Pharmaceutical and Biotechnological Products«
"All chapters are thorough and well written by leadingexperts in the particular fields. The book provides researchers andstudents in the field of pharmaceutical sciences with a thoroughunderstanding of chiral separations and offers a convenient routeto selecting best chiral separation method." (AnalBioanal Chem, 2011)
"This is an essential text for analytical and separationsscientists in the biotechnological, pharmaceutical, agricultural,and food industries, as well as students." (Laboratory Journal, 22November 2010)
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