Acetaldehyde-Related Pathology

Beschreibung

Part of the prestigious Novartis Foundation, this is the first bookto review the pathology associated with acetaldehyde, a known toxicagent found in cigarette smoke and other pollutants and derivedfrom ingested alcohol, amongst other sources. In the body,acetaldehyde affects several tissues, particularly the brain andliver, causing various diseases, including cancer, alcoholic liverdisease and Alzheimer's. Acetaldehyde-Related Pathology describes the toxiceffects of acetaldehyde at the tissue and cellular levels,reviewing enzyme biochemistry, transgenic mouse models of alcoholdehydrogenase mutants, and the cell-signalling pathways implicatedin alcohol-related pathology. It explores the mechanisms ofacetaldehyde-induced damage to tissues, often a first step incarcinogenesis, including the oral cavity, the human airway, andthe GI tract. The book considers pharmacological strategies andtreatments for reducing oral and intestinal acetaldehyde.Acetaldehyde-Related Pathology features in-depth,round-table discussions by an international array of scientistsfrom major laboratories worldwide involved in studies ofacetaldehyde-related pathology. This book is essential reading for anyone interested in theeffects of this compound - pathologists, biochemists,toxicologists, cell and molecular biologists.

Autor*in

Derek J. Chadwick

Themen in »Acetaldehyde-Related Pathology«

Biochemie Biochemie u. Chemische Biologie Biochemistry (Chemical Biology) Biowissenschaften Cell & Molecular Biology Chemie Chemistry Life Sciences Medical Science Medizin Pharmacology & Pharmaceutical Medicine Pharmakologie u. Pharmazeutische Medizin Toxicology Toxikologie Zell- u. Molekularbiologie

Stimmen zu »Acetaldehyde-Related Pathology«

"...will be found on the shelves of most scientific biomedical libraries." (Doody's Book Reviews)
()

Details

Link teilen