Dendrimer-Based Drug Delivery Systems

Beschreibung

The opportunities and challenges of using dendrimers to improve drug delivery Among pharmaceutical and biomedical researchers, the use of dendrimers in drug delivery systems has attracted increasing interest. In particular, researchers have noted that the volume of a dendrimer increases when it has a positive charge. If this property can be applied effectively, dendrimers have enormous potential in drug delivery systems, directly supplying medication to targeted human organs. With contributions from an international team of pioneers and experts in dendrimer research, this book provides a comprehensive overview of the latest research efforts in designing and optimizing dendrimer-based drug delivery systems. The book analyzes key issues, demonstrating the critical connections that link fundamental concepts, design, synthesis, analytical methodology, and biological assessment to the practical use of dendrimers in drug delivery applications. Topics covered include: * Dendrimer history * Synthesis * Physicochemical properties * Principles of drug delivery * Applications in diverse biomedical fields Dendrimer-Based Drug Delivery Systems reflects the authors' thorough review and analysis of the current literature as well as their own firsthand experience in the lab. Readers will not only discover the current state of the science, but also gain valuable insights into fruitful directions for future research. References at the end of each chapter serve as a gateway to the growing body of literature in the field, enabling readers to explore each individual topic in greater depth. Pharmaceutical and biomedical researchers will find this book a unique and essential guide to the opportunities, issues, and challenges involved in fully exploiting the potential of dendrimers to improve drug delivery.
This book focuses on the formulation and delivery of dendrimers. It offers both a comprehensive introduction and reference to practical applications. The coverage encompasses dendritic drug delivery systems ranging from dendrimers chemistry to cellular uptake of dendritic nanoparticles. With the specific application of dendrimers in drug and biologic delivery, the text highlights their versatility in solving development issues in a wide class of drugs. Discussing all the unique opportunities, issues, and challenges involved in exploiting dendrimers for improving drug delivery, this book helps pharmaceutical and related scientists understand and work with this drug carrier.

Autor*in

Yiyun Cheng

Themen in »Dendrimer-Based Drug Delivery Systems«

Biomaterial Biomaterialien Biomaterials Biomedical Engineering Biomedizintechnik Chemie Chemistry Dendrimere Medical Science Medizin Pharmaceutical & Medicinal Chemistry Pharmacology & Pharmaceutical Medicine Pharmakologie u. Pharmazeutische Medizin Pharmazeutische Chemie Pharmazeutische u. Medizinische Chemie

Stimmen zu »Dendrimer-Based Drug Delivery Systems«

"This book should be particularly valuable for everyone working in the dendrimer area, but also for researchers in drug delivery and pharmaceutical sciences more generally. To my mind, it is clearly a book to have on your shelf!." (ChemMedChem, 1 March 2013)
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