Exploration and Analysis of DNA Microarray and Protein Array Data
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Beschreibung
A cutting-edge guide to the analysis of DNA microarray data
Genomics is one of the major scientific revolutions of thiscentury, and the use of microarrays to rapidly analyze numerous DNAsamples has enabled scientists to make sense of mountains ofgenomic data through statistical analysis. Today, microarrays arebeing used in biomedical research to study such vital areas as adrug's therapeutic value-or toxicity-andcancer-spreading patterns of gene activity.
Exploration and Analysis of DNA Microarray and Protein ArrayData answers the need for a comprehensive, cutting-edge overview ofthis important and emerging field. The authors, seasonedresearchers with extensive experience in both industry andacademia, effectively outline all phases of this revolutionaryanalytical technique, from the preprocessing to the analysisstage.
Highlights of the text include:
* A review of basic molecular biology, followed by anintroduction to microarrays and their preparation
* Chapters on processing scanned images and preprocessingmicroarray data
* Methods for identifying differentially expressed genes incomparative microarray experiments
* Discussions of gene and sample clustering and classprediction
* Extension of analysis methods to protein array data
Numerous exercises for self-study as well as data sets and auseful collection of computational tools on the authors' Website make this important text a valuable resource for both studentsand professionals in the field.
Autor*in
Dhammika Amaratunga
Themen in »Exploration and Analysis of DNA Microarray and Protein Array Data«
Biochemie Biometrie Biowissenschaften Cell & Molecular Biology Genetics Genetik Life Sciences Mathematik / Wahrscheinlichkeitstheorie, Statistik Molekularbiologie Statistical Genetics / Microarray Analysis Statistics Statistik Statistische Genetik / Microarray-Analyse Zell- u. Molekularbiologie
Stimmen zu »Exploration and Analysis of DNA Microarray and Protein Array Data«
".extremely well written.a comprehensive and up-to-dateoverview of this important field." (Journal of EnvironmentalQuality, Jan/Feb 2005)
".an extensive overview of current microarray dataanalysis." (Clinical Chemistry, November 2004)
"The book would be useful to anyone studying or working with theDNA and protein arrays." (Annals of Biomedical Engineering,November 2004)
".presents an extensive series of computational, visual,and statistical tools that are being used for exploring andanalyzing microarray data." (Quarterly of AppliedMathematics, Vol. LXII, No. 1, March 2004)
".outlines methodologies for analyzing DNA microarraysand protein array data for industrial and academicapplications." (Genetic Engineering News, March 15,2004)
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