A Cell Biologist's Guide to Modeling and Bioinformatics
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Beschreibung
A step-by-step guide to using computational tools to solve problemsin cell biology
Combining expert discussion with examples that can be reproducedby the reader, A Cell Biologist's Guide to Modeling andBioinformatics introduces an array of informatics tools thatare available for analyzing biological data and modeling cellularprocesses. You learn to fully leverage public databases and createyour own computational models. All that you need is a workingknowledge of algebra and cellular biology; the author provides allthe other tools you need to understand the necessary statisticaland mathematical methods.
Coverage is divided into two main categories:
* Molecular sequence database chapters are dedicated to gainingan understanding of tools and strategies--including queries,alignment methods, and statistical significancemeasures--needed to improve searches for sequence similarity,protein families, and putative functional domains. Discussions ofsequence alignments and biological database searching focus onpublicly available resources used for background research and thecharacterization of novel gene products.
* Modeling chapters take you through all the steps involved increating a computational model for such basic research areas ascell cycle, calcium dynamics, and glycolysis. Each chapterintroduces a new simulation tooland is based on published research.The combination creates a rich context for ongoing skill andknowledge development in modeling biological research systems.
Students and professional cell biologists can develop the basicskills needed to learn computational cell biology. This uniquetext, with its step-by-step instruction, enables you to test anddevelop your new bioinformatics and modeling skills. References areprovided to help you take advantage of more advanced techniques,technologies, and training.
Autor*in
Raquell M. Holmes
Themen in »A Cell Biologist's Guide to Modeling and Bioinformatics«
Bioinformatics & Computational Biology Bioinformatik Bioinformatik u. Computersimulationen in der Biowissenschaften Biowissenschaften Cell & Molecular Biology Life Sciences Zell- u. Molekularbiologie
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"A Cell Biologist's Guide to Modeling and Bioinformatics is well written, well illustrated...this volume is a must-read for any biologist who wants an introduction to quantitative methods. It will also be a useful textbook for students." (The Quarterly Review of Biology, September 2008)
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