Integrated Genomics
A Discovery-Based Laboratory Course
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Beschreibung
Integrated Genomics: A Discovery-Based LaboratoryCourse introduces the excitement of discovery to thebasic molecular biology laboratory. Utilizing up-to-date molecularbiology protocols and a basic experimental design, this text offersexperience with three different model systems. Students will becomefamiliar with the simplicity and power of single-celled organisms,Escherichia coli and Saccharomyces cerevisiae, asthey search for genes that interact and function within thenematode Caenorhabditis elegans.
Incorporated throughout the course are exercises designed tooffer students familiarity with the wealth of bioinformatics datathat can be accessed on the World Wide Web. Following completion ofinteraction studies within the yeast, the course is designed toallow students to examine the functional consequences of reducing agene's function within the multicellular worm that is bothsimple and inexpensive to maintain within a laboratory. Theinclusion of alternative experiments allow for flexibility indetermining the ending date or goal of the laboratory, as well asworking within the available budget and resources of most anyclassroom environment.
Further striking features of this title are:
* An accompanying Web site providing PowerPoint slides, pluslinks to the internet, and regular updates as bioinformaticsdatabases evolve and methods improve. www.wiley.com/go/caldwell
* Inclusion of modern genomic/proteomic technologies such as theyeast two-hybrid system and RNAi
* Detailed experimental protocols and easy access toinstructional materials
This discovery-based laboratory course provides excellentpractical training for those pursuing career paths in biomedicine,pharmacy, and biotechnology.
Autor*in
Guy Caldwell
Themen in »Integrated Genomics«
Biowissenschaften Genetics Genetik Genomics Life Sciences
Stimmen zu »Integrated Genomics«
"I greatly admire the efforts of the authors. Their goals arepraiseworthy and this manual is well written." (The QuarterlyReview of Biology, September 2007)
"...an excellent tool for introducing a wide range ofstudents to modern concepts in molecular biology, genomics,proteomics, and bioinformatics in an integrated discovery-basedformat..." (The Annals of Pharmacotherapy, March2007)
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