Chadwick Nuclear Organization in Development and Disease

Nuclear Organization in Development and Disease

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Beschreibung

This book draws together contributions from cell and developmentalbiologists, structural biologists, geneticists and clinicalscientists aimed at a better understanding of the cellular andmolecular basis of these diseases. Topics include: * How nuclear structure and location within a nucleus affect geneexpression * Chromatin organization and cell differentiation * The nature of the interactions between the nuclear envelope andthe cytoskeleton * The extent to which the cytoskeleton mediates communicationbetween the cell membrane and nucleus in regulating gene expressionand whether disruption of such communication might underlie thedisease processes It is hoped that a better understanding of the mechanismsleading to disease pathogenesis may ultimately lead to morerational and appropriate treatments.

Autor*in

Derek J. Chadwick

Themen in »Nuclear Organization in Development and Disease«

Biowissenschaften Cell & Molecular Biology Genetics Genetik Life Sciences Medical Science Medical Sciences Special Topics Medizin Molekularbiologie Spezialthemen Medizin Zell- u. Molekularbiologie

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"...an excellent guide to research in the field of nuclear organization, and an encouragement for students interested in learning how great minds tackle complex problems." (Doody's Health Services)
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Details

ISBN: 9780470093740
Verlag: John Wiley & Sons
Erscheinung: 05.08.2005

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