Bayesian Approaches to Clinical Trials and Health-Care Evaluation

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READ ALL ABOUT IT! David Spiegelhalter has recently joined the ranks of IsaacNewton, Charles Darwin and Stephen Hawking by becoming a fellow ofthe Royal Society. Originating from the Medical ResearchCouncil's biostatistics unit, David has played a leading rolein the Bristol heart surgery and Harold Shipmaninquiries. Order a copy of this author's comprehensive textTODAY! The Bayesian approach involves synthesising data and judgementin order to reach conclusions about unknown quantities and makepredictions. Bayesian methods have become increasingly popular inrecent years, notably in medical research, and although there are anumber of books on Bayesian analysis, few cover clinical trials andbiostatistical applications in any detail. Bayesian Approaches toClinical Trials and Health-Care Evaluation provides a valuableoverview of this rapidly evolving field, including basic Bayesianideas, prior distributions, clinical trials, observational studies,evidence synthesis and cost-effectiveness analysis. Covers a broad array of essential topics, building from the basicsto more advanced techniques. * Illustrated throughout by detailed case studies and workedexamples * Includes exercises in all chapters * Accessible to anyone with a basic knowledge ofstatistics * Authors are at the forefront of research into Bayesian methodsin medical research * Accompanied by a Web site featuring data sets and workedexamples using Excel and WinBUGS - the most widely used Bayesianmodelling package Bayesian Approaches to Clinical Trials and Health-Care Evaluationis suitable for students and researchers in medical statistics,statisticians in the pharmaceutical industry, and anyone involvedin conducting clinical trials and assessment of health-caretechnology.

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David J. Spiegelhalter

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Bayesian Analysis Bayes-Verfahren Biostatistics Biostatistik Gesundheits- u. Sozialwesen Health & Social Care Health Care Administration Statistics Statistik Verwaltung im Gesundheitswesen

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"This is a terrific book and should be on the shelf of everyprofessional that works in clinical trials or health-careevaluation. It gives a thorough pragmatic introduction to Bayesianmethods for health-care interventions, provides many example alongwith data and software to reproduce the analyses, guides readers toareas where Bayesian methods are particularly valuable, andincludes an excellent set of exercises." (Journal of theAmerican Statistical Association, June 2009) "Bayesian Approaches to Clinical Trials and Health-CareEvaluation' is a clear and comprehensive text for biostatisticianswho want to understand and apply Bayesian statistical methods toclinical research." (Journal of Clinical Best Practices, Nov2008) "...an indispensable resource for all students andinvestigators who plan to incorporate Bayesian methods into theirresearch." (The Annals of Pharmacotherapy, January 2005) "...a valuable resource for libraries, and those who areinvolved in quantitative health care evaluation..." (RoyalStatistical Society, Vol.168, No.1, January 2005) "...The technical material is presented in an accessible style,and the examples given clearly illustrate the principles underdiscussion..." (Short Book Reviews, Vol.24, No.3, December2004) "...Bayesian analysis seems set to reach a wider audience withthe publication of [this] introductory level text..." (FinancialTimes, 16 April 2004) "...very well laid-out and easy to follow...a very good resourcefor teaching students..." (Statistical Methods in MedicalResearch, Vol 14, 2005) "I would use with pleasure and interest this book as atextbook..." (Metron Journal, Vol.63, No.2, 2005) "...I can pay the authors no higher tribute than to say that Iwould be proud to have written this book. It is elegant and it isdestined to becoming a classic in the field." (Statistics inMedicine, 15th July 2005) "...a generous supply of exercises...I recommend it veryhighly..." (Clinical Trials, No.1 2004) "...Bayesian analysis seems set to reach a wider audience withthe publication of [this] introductory level text..." (FinancialTimes, 16 April 2004) "...a generous supply of exercises...I recommend it veryhighly..." (Clinical Trials, No.1 2004)
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