High-Performance Gradient Elution
The Practical Application of the Linear-Solvent-Strength Model
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Beschreibung
Gradient elution demystified
Of the various ways in which chromatography is applied today, fewhave been as misunderstood as the technique of gradient elution,which presents many challenges compared to isocratic separation.When properly explained, however, gradient elution can be lessdifficult to understand and much easier to use than oftenassumed.
Written by two well-known authorities in liquid chromatography,High-Performance Gradient Elution: The Practical Application of theLinear-Solvent-Strength Model takes the mystery out of the practiceof gradient elution and helps remove barriers to the practicalapplication of this important separation technique. The bookpresents a systematic approach to the current understanding ofgradient elution, describing theory, methodology, and applicationsacross many of the fields that use liquid chromatography as aprimary analytical tool.
This up-to-date, practical, and comprehensive treatment of gradientelution:
* Provides specific, step-by-step recommendations for developing agradient separation for any sample
* Describes the best approach for troubleshooting problems withgradient methods
* Guides the reader on the equipment used for gradientelution
* Lists which conditions should be varied first during methoddevelopment, and explains how to interpret scouting gradients
* Explains how to avoid problems in transferring gradientmethods
With a focus on the use of linear solvent strength (LSS) theory forpredicting gradient LC behavior and separations by reversed-phaseHPLC, High-Performance Gradient Elution gives every chromatographeraccess to this useful tool.
Autor*in
Lloyd R. Snyder
Themen in »High-Performance Gradient Elution«
Analytical Chemistry Analytische Chemie Chemie Chemistry Chromatographie Chromatographie / Trennverfahren Chromatography / Separation Techniques
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"This book is clear, well written, and easy to understand despitethe complexity of the subject." (Journal of the AmericanChemical Society, July 2007)
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