The same careful rigour imposed on the design of phase IIIrandomised controlled trials is not always applied to medicalresearch in other areas such as trials conducted at earlier stagesof drug development.
With the emphasis that is now placed on evidence-based medicine,such care and rigour will inevitably impact on these areas withincreasing attention turned to the quality of design.
This title describes what principles can be used to structureresearch effectively allowing for the required degree ofaccuracy.
Written by two best selling authors, this book includes manyexamples from medical literature and will be of great value to allgroups conducting studies at the interface of clinical andlaboratory research.
David Machin
Heilkunde Medical Science Medizin
"...a thorough but concise introduction to study design anddata analysis." (E-STREAMS, June 2006)
"...a very good attempt to discuss various aspects ofclinical research..." (Journal of BiopharmaceuticalStatistics, July/August 2006)
"This is a well researched, well written, thoughtful,and...easy to read primer...a valuable addition to booksfor research physicians, medical students, and others..."(Doody's Health Services)
"...this book is surprisingly refreshing...could be usedin any number of situations with equality utility..."(Canadian Journal of Medical Laboratory Science, 2005)
()