Drug Absorption Studies
In Situ, In Vitro and In Silico Models
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Beschreibung
Ideal material for a huge range of professionals in drug therapeutics and research, this is a well thought-out, highly practical text covering contemporary ‘in vitro’ techniques for drug absorption studies. Starting at the molecular level of investigation, it continues with cell monolayer models (both primary and cell lines) and culminates with in situ techniques as a final testing format. In addition, chapters on high-throughput assays, in vitro-in vivo correlation, bioinformatics and regulatory issues are covered, giving a comprehensive overview of available models and techniques. Moreover, an appendix consisting of a number of practical protocols is available online, updated as needed, and should prove very helpful to apply the techniques directly to the benchside.
Comprehensively summarises the different approaches to assess drug absorption from in vitro models Gives a review on the current state-of-the-art in pharmaceutical cell biology Provides readers with helpful protocols for many applications that can be directly used at the laboratory bench
Autor*in
Carsten Ehrhardt
Themen in »Drug Absorption Studies«
Assessment Expression Transport bioinformatics biotechnology cell biology cell lines cloning medicine metabolism pharmaceuticals