Protein Misfolding, Aggregation and Conformational Diseases
Part B: Molecular Mechanisms of Conformational Diseases
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Beschreibung
Protein Misfolding, Aggregation and Conformational Diseases, Part B: Molecular Mechanisms of Conformational Diseases, is a comprehensive volume providing a broad and detailed discussion of the relationships of protein misfolding and aggregation with the pathogenesis of numerous conformational diseases. While the Part A was dedicated to the description of the general mechanisms underlying protein misfolding, aggregation, and development of protein deposition disorders, this volume summarizes recent achievements in the understanding of the molecular mechanisms of conformational diseases. Research indicates that these mechanisms are highly diverse and range from the altered protein structure leading to the enhanced propensity for aggregation/deposition or the impaired functions and ending with changes in supra-molecular structures or posttranslational modification. Protein Misfolding, Aggregation and Conformational Diseases, Part B: Molecular Mechanisms of Conformational Diseases, is an ideal book for pharmaceutical scientists, molecular and cellular biologists, biochemists, immunologists, protein scientists, and biophysicists.
The second volume continues to fill the gap in protein review and protocal literature while summarizing recent achievements in the understanding of the relationships between protein misfoldings, aggregation, and development of protein deposition disorders. The focus of Part B is the molecular basis of differential disorders.
Fills the gap of what has not been discussed in protein review and protocol books Includes supplementary material: sn.pub/extras
Autor*in
Vladimir N. Uversky
Themen in »Protein Misfolding, Aggregation and Conformational Diseases«
cell biology molecular mechanisms pathophysiology physiology post-translational modification protein structure translation