Plasticity in the Visual System
From Genes to Circuits
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Beschreibung
Plasticity is the basis for learning, memory formation and cognition, and the adaptability it affords is essential for normal day-to-day functioning. Many diseases of brain functioning can be described as, or affect, plasticity mechanisms. The goal of Plasticity in the Visual System: From Genes to Circuits is to assemble and integrate the various levels of analysis required to approach a more complete picture of plasticity in the visual system. Researchers with backgrounds varying from systems neuroscience to molecular biology present a coherent picture of visual system plasticity, in which an array of genetic and molecular processes becomes linked with changes in neuronal connectivity, physiological changes, and ultimately, learning behavior. Because of its interdisciplinary view on plasticity, this book will appeal to the wide neuroscience community.
Plasticity in the Visual System: From Genes to Circuits will advance discussion in a wide range of fields, including molecular, cellular and systems neuroscience, perceptual psychology, computational modeling and will be of use in graduate level courses and seminars in these areas.
Mechanisms of neural plasticity enable the encoding and memorization of information based on sensory inputs and can be harnessed to partially restore function after CNS assault such as stroke or head trauma. In the present book, experts from the field of visual system plasticity describe and evaluate the evidence for neural mechanisms proposed to underlie CNS plasticity in the major divisions of the brain dedicated to visual processing, the retina, sub-cortical structures and cortex. We present studies from a wide variety of disciplines that range from molecular biology to neurophysiology and computer modeling. Leading investigators discuss their own work, and integrate this research with colleagues from other specializations. The book points out future applications for this research including clinical uses and engineering within the biomedical sciences. This book is an exciting and thought provoking read for all levels of science enthusiast interested in the physical basis of learning and cognition.
Discusses retinal plasticity; directly addresses the role of immediate early genes as the first genetic outlet in the cell's plastic response; and addresses dynamic plasticity in higher order visual areas and relates them to the brain mechanisms that underlie complex behaviors Couples together findings from molecular biology, genetics, electrophysiology as well as human psychophysics Includes supplementary material: sn.pub/extras
Autor*in
Raphael Pinaud
Themen in »Plasticity in the Visual System«
Cortex gene expression genes molecular biology neural mechanisms neurophysiology perception physiology
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From the reviews:
"Plasticity in the Visual System is a compilation of work of renowned scientists into the neural mechanisms that underlie plasticity of the visual system. … The book will be appealing to neuroscientists interested in plasticity in general and particularly to those interested in the visual system. The book is also accessible to graduate students in neuroscience and offers not only a wealth of information regarding visual system plasticity and mechanisms, but also furnishes interesting new lines of research." (Maurice Ptito, The Lancet Neurology, Vol. 5, July, 2006)
"An update of recent developments trying to integrate the molecular basis of visual plasticity with changes in neuronal activity and morphology. … The book appears to be primarily written for graduate students and visual neuroscientists, including perceptual psychologists and computational modelers, who use different approaches to tackle the problem of brain plasticity, using the visual system as a model. … is a useful complement for the neuroradiology audience because it provides insight on molecular mechanisms that underlie plasticity at different levels of the visual pathway." (American Journal of Neuroradiology, January, 2007)
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