Power Laws, Scale-Free Networks and Genome Biology
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Beschreibung
Power Laws, Scale-free Networks and Genome Biology deals with crucial aspects of the theoretical foundations of systems biology, namely power law distributions and scale-free networks which have emerged as the hallmarks of biological organization in the post-genomic era. The chapters in the book not only describe the interesting mathematical properties of biological networks but moves beyond phenomenology, toward models of evolution capable of explaining the emergence of these features. The collection of chapters, contributed by both physicists and biologists, strives to address the problems in this field in a rigorous but not excessively mathematical manner and to represent different viewpoints, which is crucial in this emerging discipline. Each chapter includes, in addition to technical descriptions of properties of biological networks and evolutionary models, a more general and accessible introduction to the respective problems. Most chapters emphasize the potential of theoretical systems biology for discovery of new biological phenomena.
The first such compendium in the field Contributed by leading researchers in the field Balanced coverage of the emerging field of Theoretical Systems Biology, accessibility to researchers with limited mathematical background combined with thorough presentation Contains chapter summaries Contains detailed illustrations Includes supplementary material: sn.pub/extras
Autor*in
Eugene V. Koonin
Themen in »Power Laws, Scale-Free Networks and Genome Biology«
DNA evolution genes genetics genome mathematical modeling molecular biology protein regulation transcription Proteomics