Experimental Models of Multiple Sclerosis
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Beschreibung
Multiple Sclerosis (MS) is an enigmatic immune mediated disease of the central nervous system that affects about 350,000 individuals in the US, and many more around the world. The mechanism of this disease is largely unknown and there is no cure for it. However, there are several well-characterized experimental animal models that help us understand and speculate about potential mechanisms of pathology in this disease. Many of the experimental therapies designed for this disease rely on testing the drugs in animal models before using it in clinical trials. This book combines for the first time the different experimental models for MS (including immune-mediated and viral) under one roof, and highlights aspects that are different or shared among these experimental models. It’s aim is to improve our understanding of this devastating disease and help us think about potential additional therapies for it.
Experimental Models of Multiple Sclerosis will be an important reference for neuroscientists, neurologists, immunologists, microbiologists (especially virologists) and pathologists (especially neuropathologists). Health professionals involved with MS, and medical students will also benefit from this book.
Multiple Sclerosis (MS) is an enigmatic immune mediated disease of the central nervous system that affects about 350,000 individuals in the US, and many more around the world. The mechanism of this disease is largely unknown and there is no cure for it. However, there are several well-characterized experimental animal models that help us understand and speculate about potential mechanisms of pathology in this disease. Many of the experimental therapies designed for this disease rely on testing the drugs in animal models before using it in clinical trials. This book combines for the first time the different experimental models for MS (including immune-mediated and viral) under one roof, and highlights aspects that are different or shared among these experimental models. It’s aim is to improve our understanding of this devastating disease and help us think about potential additional therapies for it.
This is the only title on experimental models of multiple sclerosis
Autor*in
Ehud Lavi
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Antigen Chemokine Nervous System autoimmune disease interferon neurons
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From the reviews:
"A specialist book that aims to combine and present information about every existing animal model for multiple sclerosis. The target audience for this book includes neuroscientists, neurologists, immunologists, microbiologists, and neuropathologists. Clearly, some neuroradiologists … will also benefit from the information in this book. For the readers of AJNR, it is thought that a primary use of this book might be a reference for those collaborating with basic neuroscientists. … This will be a valuable resource for any scientists … ." (American Journal of Neuroradiology, January, 2007)
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