Carpenter Rational Design of Stable Protein Formulations

Rational Design of Stable Protein Formulations

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Theory and Practice

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Beschreibung

Recombinant proteins and polypeptides continue to be the most important class of biotechnology-derived agents in today's pharmaceutical industry. Over the past few years, our fundamental understanding of how proteins degrade and how stabilizing agents work has made it possible to approach formulation of protein pharmaceuticals from a much more rational point of view.

This book describes the current level of understanding of protein instability and the strategies for stabilizing proteins under a variety of stressful conditions.


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John F. Carpenter

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Glycin Oxidation Polypeptide biotechnology databases preparation primary structure protein proteins

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Details

ISBN: 9780306467417
Verlag: Springer US
Erscheinung: 30.04.2002

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